At present, primary thrombocythemia can not be completely cured, so there is no “cure program”, the main treatment options are drug therapy, surgical treatment, etc., please follow the doctor’s instructions. 1. Drug treatment: hydroxyurea is often used for treatment, and interferon can also be used for treatment. Interferon can inhibit megakaryocyte production and shorten the platelet production time, so as to achieve the effect of lowering platelets. 2. Surgery: Hematopoietic stem cell transplantation is a therapeutic means to rebuild normal hematopoietic and immune functions. The treatment of primary thrombocythemia is mainly to prevent and treat thrombotic complications, which can reduce the number of platelets through cell-lowering drugs to minimize the occurrence of thrombosis, but it cannot be completely cured at present. It is recommended that patients follow the doctor’s instructions, do not blindly self-medication.