When middle-aged and elderly people have unexplained widespread pain, weakness, fatigue, sleep disorders, and often feel “too tired”, do not think that it is poor rest from exertion, you should promptly see a neurologist, you may be suffering from fibromyalgia syndrome. Fibromyalgia syndrome is a chronic and widespread soft tissue pain syndrome that manifests clinically as pain and stiffness in multiple parts of the musculoskeletal system and pressure points in specific areas. In addition to pain and pressure points, patients may also present with sleep disturbances, fatigue and morning stiffness. Studies have shown that some patients remain in a light sleep phase and never enter a deep sleep where they can get rest. About 90% of patients have sleep disturbance, which is characterized by insomnia, wakefulness, dreaminess, and lack of energy. 50% to 90% of patients have fatigue, and about half of patients have severe fatigue symptoms, often feeling “too tired to work”. In patients with morning stiffness, the severity is related to sleep and disease activity. In addition, patients may experience numbness and swelling. Therefore, middle-aged and elderly patients who often feel “too tired” and cannot even hold on to their daily work should come to the hospital promptly for medical consultation. Fibromyalgia is an organic disease, and with active treatment, it is possible to improve the patient’s symptoms and quality of life.