Abdominal pain with difficulty in defecation is considered to be related to colitis, incomplete intestinal obstruction, constipation and other diseases, which can be treated with drugs such as Liuzosulfapyridine enteric-coated tablets, Lactulose oral solution and other medicines under the guidance of doctor. 1. Colitis: generally due to the colon tissue stimulated by inflammation, the intestinal wall blockage, edema, resulting in narrowing of the intestinal lumen, or even blockage, which in turn causes abdominal pain and difficulty in defecation, you can follow the doctor’s instructions to use mesalazine extended-release granules, salicylazosulfapyridine enteric-coated tablets and other drugs to treat. 2. Incomplete intestinal obstruction: usually due to incomplete intestinal obstruction, the intestinal contents can not pass through the intestinal tract normally, the intestinal contents of the obstruction, which in turn causes abdominal pain and difficulty in defecation, you can use lactulose oral solution, amoxicillin capsule and other medicines to treat the serious need for surgical diagnosis and treatment. 3. constipation: may be due to constipation, resulting in slow peristalsis, so that intestinal contents can not be excreted normally, which in turn causes abdominal pain and difficult bowel movement phenomenon, can be used wheat fiber granules, lactulose oral solution and other drugs to treat. Abdominal pain and difficulty in defecation may also be related to other factors such as gastrointestinal dysfunction, should be timely to the hospital for consultation, improve the examination, clarify the cause of the disease and diagnosis, standardized treatment under the guidance of the physician, avoid self-medication to avoid adverse consequences.