In case of obvious sunken cheeks, the cheek arches are seen to be bulging, the cheeks are collapsed, fine wrinkles are visible at the cheeks and corners of the mouth, the skin is dry, the complexion is yellowish and unattractive, and it is much older than the actual age. So the causes of obvious sunken cheeks are usually several? 1, missing teeth lead to muscle collapse: usually after all the teeth are missing, due to the loss of teeth support between the upper and lower jaws, and the alveolar bone or the entire jaw bone due to the lack of normal chewing force stimulation, will gradually degenerate, absorption, resulting in the height of the lower part of the face becomes shorter. 2, facial wasting: wasting leads to cheek and surrounding muscle relaxation, lips and cheeks tend to sink, resulting in sagging corners of the mouth, facial deformation and wrinkles increase, the whole person looks older than the same age. 3, aspartyl glucosaminuria: aspartyl glucosaminuria is an autosomal recessive disease caused by the lack of aspartyl amino glucosidase in the body, belonging to a kind of lysosomal disease. Wasting, like obesity, is a form of subfertility. When the body fat and protein decrease and the weight loss exceeds 10% of the normal standard, it is called wasting. The wasting referred to here is generally progressive in the short term, with weight loss before and after the measured weight value, and there is obvious evidence of looser clothes, looser belts, larger shoes, as well as subcutaneous fat reduction, muscle weakness, skin laxity, bone prominence and so on.