How much do you know about mastocytosis?

  Breast pain (mastalgia, breast pain) is a concept currently recognized abroad in the field of breast disease specialization and refers to a situation in which a patient has a complaint of breast pain and discomfort, but no definite abnormality is found on examination. It can be both a symptom and a diagnosis. Breast pain may originate from a physiological disorder that may be related to stress, smoking, excessive intake of saturated fatty acids, changes in hormone levels, and other factors, and its exact etiology is not known. Breast pain disorder is widespread in the population, with more than 2/3 of women having experienced breast pain discomfort. The diagnosis of breast pain disorder is made after a series of reasonable tests to rule out benign breast lesions and breast cancer.  The prognosis of clearly diagnosed breast pain is generally considered good and patients need not worry about it, but the painful discomfort often contributes to the patient’s negative emotions, which may increase the patient’s inexplicable fear of developing a malignant tumor and seriously affect the patient’s quality of life. The treatment of breast pain disorders focuses more on the social and psychological aspects, and there is also a clear benefit of giving appropriate medical interventions to some specific patients.  Traditionally, in our medical practice, “breast enlargement” usually includes the following two scenarios: one is a painful and uncomfortable visit to the breast, with diffuse thickening and uneven texture on palpation (or not), with no obvious palpable masses or nodules, or a nodular feeling but no cysts or nodules on imaging. or nodules, and after the above examination, definite benign breast lesions and breast cancer are excluded. This scenario is very similar to the concept of breast pain. The second scenario is when the patient comes to the clinic with a self-perceived breast mass, with or without breast pain, and a diffuse or heterogeneous thickening of the breast gland on palpation, sometimes with a palpable mass or nodular sensation. Imaging examinations have suspicious cysts and/or nodules, or show only disorganized glandular structures on imaging; if pathological examinations are available, the results are mostly cysts, sweat gland hyperplasia, mild glandular hyperplasia, adenopathy, sclerosing adenopathy, ductal hyperplasia, and hyperplastic nodule formation, to name a few.  The main difference between the above two conditions is pathology, which can be classified as mastocytosis if there is no clear pathological abnormality, while mastocytosis encompasses many different scenarios of benign breast lesions.  The principles of treatment for breast pain are similar to those of the traditional treatment of “mastopexy”. Because there is no clear organic lesion, the main focus of treatment is to relieve symptoms and treat the symptoms. The main treatment points include: avoiding adverse emotional stimulation, maintaining an optimistic and calm state of mind, avoiding excessive work and family stress, and reducing stress at the right time; fully understanding that breast pain or “breast enlargement” is not cancer and has no impact on life and health, and putting down the burden of thought; optimizing the structure of the diet, eating less fats and oils with high saturated fatty acid content Avoid the abuse of estrogen-containing health and beauty drugs and the inappropriate intake of exogenous hormones; develop good work and rest habits, do not smoke and reduce the intake of caffeine; exercise properly to improve immunity and prevent obesity; carry out relevant physical therapy, conduct self-examination of the breast on time, regularly go to regular hospitals for re-examination, and seek early medical treatment when abnormalities are detected; Chinese medicine Chinese medicine, etc. Chinese medicine is very profound and has many classical discussions on the management of breast pain, which patients can refer to as appropriate.  Studies at home and abroad have found that emotions have a great influence on the sensation of breast pain, and that regulating emotions is an important part of the treatment of breast pain or “breast enlargement”. When cancer was ruled out, verbal reassurance alone could relieve 86% of mild pain and 52% of severe pain. This shows how great the impact of thought baggage can be on breast pain and discomfort.  Some foreign studies have found that certain endocrine therapeutic drugs can also relieve the symptoms of breast pain to some extent, such as bromocriptine, triamcinolone, certain androgens, etc. Non-endocrine drugs (such as iodine, etc.) also have certain efficacy, but these drugs are less applied in China.  Since breast cancer is closely related to changes in hormone levels, we would like to emphasize once again that you should not trust some unidentified cottage beauty pills, which may secretly add sex hormones to make you more beautiful in the short term, but the risk you take may not be worth the loss.  It is important to note that breast pain can be relieved, but breast nodules basically do not subside on their own. For benign nodules with “breast hyperplasia”, you do not have to force the nodules to “dissipate”, as long as the painful symptoms are relieved.  The standard review requirements for mammograms are generally to review the mammogram every 3 to 6 months, and mammograms can be done every 2 years for those over 40 years old.