With the increase of chronic diseases in the elderly, the research related to cardiovascular diseases is getting more and more attention. The following is a research report on the relationship between fatty liver and atherosclerosis by Chinese and foreign scholars. I. Professor Ning Guang of Ruijin Hospital, Shanghai Jiaotong University School of Medicine reported that carotid intima-media thickness (CIMT) increased and arm-ankle pulse wave velocity (ba-PWV) increased in middle-aged and elderly patients with non-alcoholic fatty liver disease (NAFLD) in China, suggesting that NAFLD is associated with atherosclerosis. Yuan Gang, Department of Hepatology, Ningbo Second Hospital, Ningbo, China The investigators included 8622 subjects aged ≥40 years from Shanghai, and used ultrasonography to detect NAFLD, CIMT and ba-PWV and to assess the relationship between them. The results showed that 30% of the subjects had NAFLD, 30.3% of men and 29.9% of women. CIMT (0.594 mm vs. 0.578 mm, P<0.0001) and ba-PWV (1665 cm/s vs. 1558 cm/s, P<0.0001) were significantly higher in patients with NAFLD compared to those without NAFLD, and both were higher in patients with NAFLD with metabolic syndrome. and ba-PWV values were increased by 35% and 30%, respectively, in patients with NAFLD, and their relationship was independent of traditional atherosclerotic risk factors and not related to metabolic syndrome. II. A retrospective cohort study in Korea showed that homeostatic model insulin resistance index (HOMA-IR), fatty liver and coronary artery calcification (CAC) score >0 were associated. The study included 10,153 patients, all of whom underwent ultrasonography to assess fatty liver and cardiac CT to assess CAC score, and defined ≥75th percentile (P75) as insulin resistance (IR) in the evaluation of HOMA-IR. The results showed that 915 patients with CAC score >0 had increased metabolic syndrome-related indicators such as blood glucose, blood pressure, triglycerides, and waist circumference, and decreased HDL cholesterol levels. 55% of patients with CAC score >0 had fatty liver and 33.7% had IR. The study showed that fatty liver, HOMA-IR, and the combined presence of both were associated with CAC score >0 and could be an The study showed that fatty liver, HOMA-IR and the combination of both were associated with CAC score >0 and could be an independent risk factor for atherosclerosis.