Vesiculitis often occurs simultaneously with prostatitis and is mostly due to retrograde infection. The pathogenic bacteria are mostly Staphylococcus aureus, Streptococcus haemolyticus and Escherichia coli, and are divided into two categories: acute and chronic vesiculitis. 1. Etiology Retrograde infection through the urethra, bacteria from the urethral opening, vas deferens invade the seminal vesicle gland. When the prostate, rectum, bladder and other organs adjacent to the seminal vesicles are infected, bacteria can spread directly to the seminal vesicle gland. In internal infections, bacteria can spread to the seminal vesicles through the bloodstream. 2. Clinical manifestations Seminal vesiculitis is one of the common infectious diseases in men, with the onset of the disease mostly in the age of 20 to 40 years, with hematospermia as the main clinical manifestation, but there are acute and chronic, with great individual differences and different clinical manifestations. (1) Pain In acute cases, pain in the lower abdomen is seen and involves the perineum and both groins. In chronic cases, vague pain in the suprapubic region with perineal discomfort can be seen. The painful symptoms are significantly increased during ejaculation. (2) Urinary frequency, urgency, painful urination In acute cases, symptoms of urinary urgency and painful urination are obvious, and difficulty in urination can be seen. In chronic cases, frequency and urgency of urination with discomfort and burning sensation are obvious. (3) Hemosperm The manifestation is the discharge of bloody semen during ejaculation, and the semen is pink or red or with blood clots. In acute cases, the phenomenon of bloody semen is more obvious. (4) Other symptoms There may be fever, chills and chills, which are the systemic symptoms seen in acute vesiculitis. Hematuria, too, is one of the manifestations of acute vesiculitis. The painful ejaculation, low libido, seminal emission and premature ejaculation are seen in chronic cases. 3, examination (1) semen routine examination A large number of red blood cells, white blood cells semen culture can be found pathogenic pathogens typical symptoms. The ejaculation may be accompanied by loss of libido, seminal emission, premature ejaculation or painful ejaculation, which is most obvious at the moment of ejaculation. In chronic vesiculitis, the pain can last for a long time, while in acute vesiculitis, abdominal pain can be caused if the adjacent organs are infected. (2) Seminal vesicography Ultrasonography (3) CT and MRI scans Spermography is mostly performed under general anesthesia or during scrotal exploration. Although the success rate is high, it is difficult to be widely used because it causes great damage to the vas deferens and cannot be used repeatedly, which may cause infertility. (4) Auxiliary examination Routine examination of semen shows a large number of red blood cells and white blood cells. Bacterial culture of semen is positive. In the routine blood test, a significant increase of leukocytes in the blood is seen in acute cases. In patients with seminal vesiculitis, enlarged seminal vesicles can be palpated with tenderness when doing anal finger diagnosis. Mild pressure pain in the lower abdomen, perineum and suprapubic area may also be present. 4.Diagnosis According to the symptoms of patients with acute prostatitis, there is a history of hematospermia; the seminal vesicles are swollen with fluctuation and tenderness during rectal examination; the seminal fluid routine examination shows a large amount of red blood cells; seminal fluid cytology examination to exclude tumor and tuberculosis; seminal vesiculography can make a clear diagnosis. 5. Treatment In the acute stage, antibiotic treatment is the main treatment. For chronic vesiculitis, comprehensive treatment with antibiotics, hot water sitz bath, estrogen and symptomatic support.