Fracture pain sleeplessness can be treated by the following methods: first, oral pain medication or intravenous use of pain medication, oral pain medication such as tramadol hydrochloride extended-release tablets, aminoglutethimide tablets, intravenous use of pain medication such as Kefir and Nisong. Through the treatment of pain medication, the patient’s pain symptoms can usually be relieved rapidly in about 30-60 minutes. Second, if there is obvious swelling at the fracture site, continuous cold compress treatment should be applied, and the pain symptoms will also be gradually relieved by cold compress for 1-2 hours in general. If it is a limb fracture, the limb should be elevated continuously to promote the local swelling to subside, which can gradually reduce the pain symptoms. With the above methods, the pain caused by the fracture can be relieved in the short term and normal sleep can be restored. Rehabilitation training is also needed during daytime rest to promote fracture healing, which can prevent painful symptoms caused by fracture at night.