Fatigue is the inability of the physiological processes of the body to sustain their functions at a specific level or the inability of the organs to maintain their intended intensity of movement, commonly known as “the body can’t take it anymore”. The things that can be done before suddenly can not be done, or want to do but can not do, energy can not focus, from the depths of their own doubts and fears, continuous physical or mental fatigue to reduce the efficiency of work, usually their own explanation is: I am not in shape today. This phenomenon is fatigue. Short-term fatigue is a natural physiological phenomenon. In daily life, some people feel very fatigued from time to time due to busy work, stressful life, heavy study load and other reasons. In general, patients who feel fatigue can recover after a few days or a week. If the fatigue lasts for more than one month, it can be considered as continuous fatigue; if the fatigue symptom lasts for 3 months, you should go to the hospital for consultation. Fatigue that lasts for more than six months and is accompanied by muscle pain, headache, low fever, poor concentration, memory loss, depression, night sweats, weight change, sore throat, pain in several joints, difficulty in recovering physical strength even after sufficient sleep, fatigue that lasts for a long time after exercise and other symptoms, such fatigue may be an early warning signal of a disease, to be precise, may be suffering from chronic fatigue Syndrome. In 1988, a new disease was added to the spectrum of human diseases – chronic fatigue syndrome (CFS). The U.S. Centers for Disease Control and Prevention (CDC) officially named the disease and formulated the corresponding diagnostic criteria. CFS is highly prevalent and dangerous. Epidemiological surveys suggest that the incidence of CFS in the population is about 0.2-0.7%, with a prevalence in the 20-50 age group and a prevalence in women. Experts from the Institute of Microbiology under the Russian Ministry of Defense estimate that at least 5% of the world’s population suffers from CFS. 40,000 to 80,000 people in the United States are suffering from CFS. The annual gross national product of the United States is reduced by$9.1 billion as a result. Statistics from the UK show that the economic loss per CFS patient for 3 months is about £3,515. The Japanese Ministry of Labor announced in March 2000 that 1/3 of Japan’s working-age population suffers from CFS, and according to the World Health Organization, CFS is one of the top five reasons for people to visit a doctor in Western developed countries. the incidence of CFS in China is 10-20% in urban areas, and up to 50% among experts, professors, intellectuals, business managers, and leading cadres. Experts such as Martin Lennan of the United States have published an article in the world medical journal Chronic Infectious Diseases and Clinical Practice that this is an important global problem. The U.S. Centers for Disease Control and Prevention has classified this disease as the first in the category of infectious diseases, grouped with cholera, malaria, hepatitis C and tuberculosis as a preventive type, and predicts that it will become one of the major diseases affecting human health in the 21st century. The World Health Organization has classified this disease as a modern and difficult disease, and since 2001, it has been holding an annual thematic conference dedicated to the prevention and treatment of CFS. In many of China’s major cities, tertiary hospitals have also opened fatigue clinics or slow fatigue specialties.