Although the diagnosis of premature ejaculation is based primarily on medical and sexual history, a brief, comprehensive examination should be performed at the initial visit to rule out possible risk factors or co-morbidities. These factors can cause premature ejaculation, aggravate premature ejaculation, or be comorbid with premature ejaculation. Of course, the need for these tests should be selected by a male or urologist experienced in the management of premature ejaculation based on the patient’s specific situation. The classification of premature ejaculation based on medical and sexual history can provide a good clue for the subsequent examination. 1. Specialist physical examination Physical examination is necessary for the initial evaluation of premature ejaculation in order to identify premature ejaculation or other sexual dysfunctions, especially underlying diseases related to erectile dysfunction. Premature ejaculation and erectile dysfunction are often concomitant disorders. These examinations include examination of male secondary sexual characteristics, penis, testicles and epididymis, and sometimes even ultrasound examination of prostate and seminal vesicles is required. 2. Urine examination When a UTI is suspected, a routine urine examination should be performed first to rule out the possibility of a urinary tract infection. If necessary, a urine bacterial culture, mycoplasma, chlamydia, gonococcus and other tests should be performed to determine the causative agent. The actual fact is that you can find a lot of people who are not able to get a good deal on a lot of things. The “two-cup” method of bacterial culture is a diagnostic procedure. Although the causal relationship and mechanism between prostatitis and premature ejaculation is unknown, current research suggests that prostatitis may be one of the risk factors for premature ejaculation and should be given proper examination and treatment. 4. Blood sex hormone examination Changes in blood sex hormone levels may lead to premature ejaculation or non-ejaculation, and there is a correlation with erectile dysfunction. Although hyperthyroidism is one of the risk factors for premature ejaculation, thyroid function tests are not recommended for patients with premature ejaculation. Symptomatic hyperthyroidism can be easily detected by clinical observation (irritability, tremor, night sweats) and heart rate monitoring, and thyroid hormone level testing should be performed only when necessary. 6.Neurophysiological examination Neurophysiological examination includes measurement of penile vibratory sensation and sensory evoked potentials of the dorsal penile nerve. It is especially important to emphasize that the current national and international guidelines for the treatment of premature ejaculation agree that neurophysiological examinations should only be completed under the guidance of specific results of medical history or physical examination and are not recommended for routine examination. After talking about so many optional tests, you may be dazzled and unable to choose. It’s okay, don’t bother, leave the questions to your doctor, take the first step, walk into the doctor’s office and say goodbye to the “rush”.