Diabetes is a chronic, lifelong disease that generally cannot be stopped, but obesity-related type 2 diabetes may get diabetic remission after intensive treatment and maintain normal blood glucose without medication. In diabetes in general, if the pancreatic islet function damage is severe, the possibility of stopping medication is very small, and long-term medication is needed to maintain blood glucose in the normal range to avoid diabetes-related complications. However, if the diabetes is detected early, with mild pancreatic islet function damage, or obesity-related type 2 diabetes, it is possible to get diabetes remission through intensive lifestyle intervention, short-term insulin intensive therapy, and metabolic surgery, etc., and maintain normal blood glucose without medication. In daily life, diabetic patients should monitor their blood glucose regularly, and go to the hospital promptly if their blood glucose value is abnormal.