Betel nut is a class I carcinogen, and long-term consumption of betel nut does carry a high risk of cancer, especially oral cancer and digestive system cancer. The main reason is that betel nut contains bio-chemicals and its rough texture will cause irritation to the oral cavity and digestive system, and long-term consumption may lead to mucosal lesions and increase the chance of cancer. At the same time, betel nut has a certain addictive nature, making it difficult to quit and increasing the amount of betel nut consumption, thus increasing the damage to the human body.1. Biotoxicity: betel nut contains a large amount of betel nut alkaloids, this alkaloid will cause rapid apoptosis of epithelial tissue cells, and increase the chances of cell mutation. In addition, betel nut also contains betel nut tannin, nitrosamines and reactive oxygen species, which have certain genotoxicity and may lead to cell mutation, thus causing cancer. At the same time, commercially available betel nut will also add lime, Lao leaves, tobacco and other substances, which can further increase the stimulation of the oral cavity and digestive system; 2, mechanical damage: eating betel nut will have a lot of coarse fiber friction oral mucosa, long-term may lead to oral mucosal damage, the lighter will induce inflammatory diseases and mucosal lesions in the oral cavity, the heavier may produce oral mucosal fibrosis, increasing the chance of cancer The more serious cases may produce oral mucosal fibrosis and increase the chance of cancer. At the same time, long-term betel nut eating will produce a certain degree of damage to the periodontium, resulting in gum recession, tooth wear, and in serious cases, tooth loss, making it impossible for patients to eat normally. In addition, eating betel nut will inevitably swallow part of the betel nut residue, into the digestive system of betel nut residue, can stimulate the local mucosa, in the long run, resulting in mucosal damage, inflammation, ulcers and other manifestations, increasing the risk of cancer; 3, other: eating betel nut has a certain degree of addiction, can stimulate nerve excitement, in order to pursue this stimulating feeling, people will increase the amount of betel nut eating, the damage to the body has also been increasing The betel nut is more likely to develop cancer. In addition to eating betel nut, some people also have bad habits such as smoking and drinking a lot of alcohol, and these stimuli are repeatedly superimposed and together lead to the occurrence of cancer. Therefore, it is not recommended to eat betel nut, and even less recommended to eat betel nut for a long time. People who already have the habit of eating betel nut are recommended to consciously avoid eating betel nut and try to replace it with other foods when they want to eat it. If the problem is more serious or has already occurred oral and digestive system problems, should actively seek medical help, early examination and treatment.