During the application of levofloxacin hydrochloride, the symptoms of hematuria should be considered the possibility of adverse drug reactions and other diseases. 1. Adverse drug reactions: after the application of levofloxacin hydrochloride, some patients may develop blood diseases such as thrombocytopenia, hemolytic anemia, and other adverse reactions such as vascular and serum sickness. The appearance of such diseases may lead to the symptoms of hematuria. 2. Other diseases: such as external injuries, urethritis, urinary stones, prostatitis, urinary system tumors and other diseases, may also trigger the symptoms of hematuria. The reason for this symptom is relatively complex; it is recommended that patients seek medical examination as soon as possible to confirm the cause of the disease, and under the guidance of the doctor for treatment.