Patients who have a new crown usually do not have symptoms of urticaria, but we can not completely exclude the possibility of urticaria complication in patients with a new crown, and the current clinical data do not support that a new crown will necessarily lead to urticaria. New crown is new coronavirus pneumonia, mainly due to the human body infected with the new coronavirus caused by a highly contagious disease, the main clinical symptoms include dry cough, fever, respiratory difficulties, etc., there are clinical data show that some of the patients with the new crown will cause a rash and other phenomena, but there is no inevitable link between the clinical evidence and urticaria. Urticaria is a kind of allergic disease, mostly due to environmental factors, such as hot and cold stimulation, sun exposure, etc. The main clinical symptoms include itching, red air masses, etc., which can be treated by oral histamine drugs, such as cetirizine hydrochloride and other drugs for anti-allergic treatment. There is no clear link between the new crown and urticaria in clinical observation. If urticaria occurs after the patient suffers from the new crown, it is mostly considered to be caused by other reasons, and the patient should actively cooperate with the doctor to carry out the treatment. Tip: The terms “new coronary pneumonia and new coronary virus pneumonia” mentioned in this article were renamed to “new coronary virus infection” on December 26, 2022, as announced by the National Health Commission.