The differential diagnosis of meningioma and glioma is as follows: 1. Different clinical symptoms: Meningioma mostly has a long course and slow onset, with mild symptoms, but optic papilledema is more common. Glioma mostly has a short course and fast onset, manifesting as headache, vomiting and limb disorders. However, symptomatic manifestations cannot completely distinguish meningioma and glioma; 2. Different imaging: CT and MRI can distinguish meningioma and glioma. Magnetic resonance can identify whether the tumor is benign or malignant lesion, and PET-CT of head and whole body can identify benign or inflammatory intracranial tumor and other lesions.