Lower extremity arterial occlusive disease is also known as lower extremity arterial occlusive disease. The main clinical symptoms include swelling, pain, localized skin redness and blackening of the proximal limb (the end close to the heart), etc. In most cases, patients can improve their symptoms after systematic treatment. The development of lower limb arterial occlusive disease is mainly due to hypertension and hyperlipidemia, which cause damage to the endothelium of the arterial vessels and lead to the formation of plaques in the walls of the vessels, resulting in narrowing and blockage of the arterial lumen, causing ischemic disease in the lower limbs. The clinical manifestations are mainly symptoms of ischemia in the lower limbs. In the early stage of the disease, most of the patients have no obvious symptoms or the symptoms are relatively mild, and they may have coldness, swelling, local skin redness, abnormal sensation, and easy fatigue when walking or moving the affected limbs. Patients may also experience intermittent claudication, limb pain, and other symptoms, and pain in the affected limb at rest, mostly at night or when lying down. Arterial occlusion of the lower extremities also leads to obstruction of blood circulation in the affected extremities, which affects the normal metabolism of the legs and may lead to irreparable skin damage, ulcers, and even gangrene in severe cases. If the infection is complicated by anaerobic bacteria, gangrene (skin can be blackened) may also occur, which can lead to death in severe cases. Patients should seek medical treatment in a timely manner. The main goal of treatment is to enhance blood flow to the affected limb and improve local tissue ischemia and hypoxia, thereby relieving the patient’s discomfort, restoring the function of the limb, and improving the quality of survival, etc. However, due to the different severity of each patient’s disease, the prognosis after treatment varies. If treatment is started in the early stages of the disease, most cases can be cured well, but when the disease progresses to a serious level such as limb necrosis, only surgical amputation can be used. In daily life, once the lower extremity arterial occlusion occurs, you should seek medical treatment in a timely manner, pay attention to keep warm, but avoid using high temperature water to soak your feet to avoid aggravating the symptoms of lower extremity ischemia. Pay attention to maintain a good lifestyle, avoid eating too much fried food, exercise regularly, quit smoking and drinking.