The minimum requirement for pain treatment is to achieve pain-free sleep; the real meaning of improving patients’ quality of life should include: pain-free sleep, pain-free rest, and pain-free activities. Myth 2: Long-term use of narcotic painkillers can lead to “addiction” “Addiction” is characterized by a continuous and unscrupulous craving for opioids, not for pain relief, but for “euphoria”. “. Pain management efforts have resulted in a significant increase in the use of opioid pain medications, yet the number of opioid abusers has shown a downward trend, and the medical use of opioid pain medications has not increased the risk of opioid abuse. Myth 3: Taking large doses of opioids can be toxic There is no capped dose of opioids, and the appropriate dose for pain relief is the dose that provides adequate analgesia and no intolerable side effects during the duration of action. The pain is not effectively relieved for a long time, which will affect the sleep and appetite, and reduce the patient’s resistance, thus giving the disease a chance to develop further. Pain can mostly be well controlled by oral medication. Myth 5: The higher the dose of morphine, the more serious the condition. Pain is a “subjective” feeling with significant variability; the dose of painkillers required for the same intensity of pain is not necessarily the same; some patients need high doses of morphine to achieve the purpose of pain control; the dose of morphine does not reflect the severity of the disease, let alone estimate the length of survival. [Myth 6] You can skip the next dose of morphine when you are not in pain Depends on different situations. If the patient is completely unconscious, refusal may be unreasonable. In this case, it is necessary to continue to persuade him/her to receive morphine. On the other hand, if the blurred consciousness is related to paranoia (feelings of threat or persecution), even mild persuasion can worsen the condition. If the patient is suspected of having delusions of victimization, morphine should no longer be used; instead, help should first be sought by telephone from his physician or home bed nurse. If it is due to confusion rather than intentional refusal to take morphine, there should be a reason to reduce the amount of morphine. The patient may be right: morphine causes drowsiness or nausea that is difficult for him to accept; or severe adverse effects such as intractable constipation, so that perhaps one state of suffering is exchanged for another, i.e., the adverse effects caused by taking morphine are even more painful than the pain. In this regard, the dosage of morphine needs to be reduced as appropriate. Obviously, it is necessary to explore the causes, or to understand the various possible reasons behind the refusal to take morphine, and also to seek expert advice and help.