Patient: I am 26 years old, female. in the middle of May 2008, I had alternating pain in both knees, which increased at night. The pain in the left elbow lasted for two days, swollen and could not be straightened, then relieved on its own. On June 2, 2008, the results of laboratory tests were negative for anti-chain “0”, rheumatoid factor 110, C-reactive protein 9.8, and blood sedimentation 50. Due to the initial onset of the disease, the secondary hospital diagnosed rheumatoid arthritis. I was treated with intramuscular penicillin twice in the morning and evening for 15 days. First of all, please help me to confirm the diagnosis and then treat my condition. Wang Yu, Department of Rheumatology and Immunology, Peking University First Hospital: Our diagnosis of rheumatoid arthritis requires clear joint examination and x-ray, as well as the exclusion of other connective tissue diseases that cause joint symptoms. It is best for patients in Beijing to come to the clinic, but also to improve the relevant tests, so as to treat the symptoms, you can come to the clinic according to your time.