A new study analyzes the effect of certain birth and infancy parameters on breast slice density. The latter is an important marker of breast cancer risk. This result showed that women over 39 years of age who gave birth and before puberty had higher breast density than normal tall and thin women. This makes it an increased risk of breast cancer. Although the role of breast slice density in breast cancer has been known for many years. But Carlos III Health Institute researchers are now leading a study to explore the effects of certain parameters on breast slice density. These include the proportion of white areas in the breast slice. He is an important breast cancer risk marker. The study was published in the Journal of Breast Cancer Research and Treatment. This study included 3574 women aged 45 to 68 years. It was assisted by a screening program in seven Spanish autonomous communities (Aragon, the Balearic Islands, Castilla-León, Catalonia, Galicia, Navarra and Valencia). Virginia Lope, first author of the study and an investigator at the National Center for Epidemiology of ISCIII, explained that continuous exposure to hormones has been a major factor in the development of the study. He explained that when continuously exposed to hormones and early life stage growth factors, the breast begins to develop a pathological breast tissue component that affects the probability of developing cancer in adulthood. A powerful biomarker. At the 2010 American Association for Cancer Research annual meeting, multiple studies were presented to support other findings published in previous years. This study showed that women with 75 percent or higher breast slice density were five times more likely to develop breast cancer than those with lower density. In addition, the study showed that women who experienced a reduction in breast density over a six-year period were at less risk than those who still had high density. Although breast density is clearly inherited, other factors have an impact. These include the age of having the first child and the number of children born. The authors therefore conclude that some studies have used breast slice density to investigate the possible effects of other exposures on breast cancer risk.