Drug rash, also known as drug dermatitis, is an inflammatory skin lesion of the skin and mucous membranes caused by drugs entering the human body through various ways such as oral intake, injection, inhalation, etc., and in severe cases, it may involve other systems of the body. The main treatment method is to stop using allergenic drugs, topical drugs, systemic drugs, etc.. 1. Discontinuation of allergenic drugs: the first step in the treatment of drug rash is to discontinue the use of allergenic drugs, including suspected allergenic drugs, be cautious of using structurally similar drugs, to avoid cross-allergy or polyvalent allergy, and drink plenty of water to accelerate the discharge of drugs. 2. Topical drugs: local erythema and papules can be used externally with glycerite lotion or glucocorticoid cream, and intermittent wet compresses can be applied to those with vesicles and oozing, and zinc oxide oil can be used externally. 3. Systemic medication: after stopping the sensitizing drugs for mild drug rash, antihistamines, vitamin C and calcium can be given, and small doses of prednisone can be given when necessary. After the appearance of drug rash, should consult a doctor in time, under the guidance of the doctor with medication, do not unauthorized use of drugs.