Lung cancer stage II, what to do

Patients with lung cancer are recommended to have a full imaging workup (clinical staging workup, especially accurate N-staging), which is necessary for adequate evaluation, and to develop a treatment plan and…

For patients with stage 2 lung cancer, the preferred treatment option is surgery, which includes lobectomy, combined lobectomy, or total pneumonectomy combined with systemic hilar and mediastinal lymph node dissection and sampling. Postoperative adjuvant chemotherapy treatment is recommended for patients with completely resected stage 2 lung cancer. When the tumor invades the mural pleura or chest wall the entire chest wall should be resected at least 2 cm from the upper and lower margins of the nearest rib of the lesion, and the length of resection of the invaded rib should be at least 5 cm from the tumor, and curative synchronous chemoradiotherapy should be given for unresectable cases.

For patients with stage 2 lung cancer with positive margins, reoperation is recommended, and if inoperable, postoperative chemoradiotherapy can be given. For patients with complete resection of stage 2-3, postoperative adjuvant chemotherapy with platinum diphtheria is recommended.

Anatomic lung segmental or wedge resection plus systematic hilar and mediastinal lymph node dissection or sampling may be considered in patients with advanced age or low lung function.