Married for more than two years, but the woman has not been able to conceive successfully called primary infertility; after the marriage of the wife successfully conceived, but due to some reasons after the spontaneous abortion failed to continue to conceive successfully called secondary infertility, which is mostly related to the female reproductive organs pathology. Married for two years, no contraception, normal sex life, normal menstruation, but always “pregnancy” is not good, this is why? Female factors (1) Vaginal diseases Vaginitis can be a “killer” of infertility if it remains untreated. Inflammatory secretions analyzed by the inflammation will not only change the vaginal environment, so that the sperm is not easy to survive, but also phagocytosis of sperm, reducing sperm motility, affecting conception. (2) Cervical Disease Narrowing of the cervical opening can affect the entry of sperm into the uterus to unite with the egg, which can usually only be detected during ultrasound examination. Another condition that is easier to observe is cervicitis. The mucus secreted by cervicitis can prevent sperms from passing through, but its symptoms are obvious: firstly, the leukorrhea will become sticky and thick, and secondly, there will be pain and bleeding during sexual intercourse, and you should go to the hospital immediately if you have this phenomenon. (3) Tubal blockage Menstrual disorders are mostly caused by endocrine disorders, which are not directly related to tubal blockage. Therefore, many people do not realize that they have tubal blockage at the early stage of the disease, and only find out that they have not yet succeeded in conceiving after 2 or 3 years. Tubal blockage will not only affect the success rate of conception, but also increase the possibility of ectopic pregnancy. (4) Ovaries Poor ovulation, early rupture of follicles, or premature ovarian failure, or polycystic ovaries, will reduce the success rate of conception. Male factors (1) Sexual dysfunction Impotence, frequent spermatorrhea, ejaculation, will make the sperm can not enter the vagina normally and induce infertility. (2) Reproductive diseases Azoospermia, oligospermia, necrospermia and other diseases are also a major “killer” of infertility. This can only be found after examination. Therefore, if a couple has not been able to conceive for 2 years, not only the woman should be examined, but also the man. (3) What to do if it is difficult to conceive? Firstly, as a precautionary measure, in order to have a more harmonious life after marriage, a full body check-up should be done before marriage, so as to know what potential pitfalls exist in oneself. Secondly, nowadays people are paying more and more attention to eugenics, so you can go to the hospital to do a pre-pregnancy physical examination six months before you are ready to conceive. If you are planning to have a second child, you should do this step even better, and it is for both of you. Thirdly, for those who have problems during the checkup, do not give up the treatment because of the trouble, and make sure that you can only plan to get pregnant after you have been cured.