It has been suggested that gonorrhea is most associated with male infertility. The mechanism of occurrence includes genital organ lesions and reproductive tract lesions, such as gonorrhea-induced orchitis and epididymitis, or gonorrhea-induced male urethritis, vesicoureteritis, vasculitis, prostatitis, and urethral stenosis occurring at a later stage of the reproductive tract caused by stenosis and atresia can be secondary to infertility. The main complication of gonorrhea in women is gonorrheal pelvic inflammation, in which chronic inflammation of the fallopian tubes can cause tubal adhesion, blockage, fluid accumulation, etc., often resulting in infertility or ectopic pregnancy. The higher the number of gonococcal infections, the higher the incidence of infertility. In addition, gonorrhea can jeopardize the next generation. If a pregnant woman is infected with gonorrhea, a small number of them can cause infection in the amniotic cavity or postpartum sepsis, etc. The fetus can be infected or its development can be impaired in the uterus, leading to preterm delivery, stillbirth or neonatal sepsis, neonatal gonococcal conjunctivitis and so on.