The cause of high CA125 in adenomyosis is not very clear and may be due to prolonged inflammation. Women with adenomyosis are likely to have increased levels of CA125. The cause of elevated CA125 is not clear. High CA125 in adenomyosis is not necessarily caused by a tumor, but may be due to long-term inflammatory stimulation. CA125 is not a specific marker for adenomyosis. Diagnosis of adenomyosis requires a combination of other tests, such as ultrasound and gynecological examination. Don’t panic if you have a high CA125 in adenomyosis, and actively cooperate with the treatment after the diagnosis of adenomyosis. Follow up closely in the obstetrics and gynecology clinic and review regularly.