1.Determine whether it is nephrotic syndrome Diagnosis is made through urine routine, 24-hour urine protein quantification, plasma albumin and blood lipid level. 2 .Determine the cause of the disease Determine whether the cause is primary, secondary, or hereditary through clinical and laboratory tests? 3.Diagnosis of clinical typing According to whether the child has hematuria, hypertension, renal insufficiency and hypocomplementemia, determine whether the disease is simple or nephritic. 4.Hormone efficacy determination Determine whether the child is hormone sensitive or hormone resistant according to the child’s urine protein turning negative after taking hormone treatment. 5.Determine the type of renal pathology For children with secondary or suspected hereditary disease, or those with clinical manifestations of nephritis, or those who do not respond well to hormone therapy, it is recommended to perform renal biopsy to determine the type of renal pathology in order to give accurate treatment. 6. Determine whether the child has comorbidities Common comorbidities include infection, blood clots, electrolyte disorders, acute renal insufficiency, etc.