Patient: My myopia is 3.75 left and 4.50 right. In 2003, I had a pneumatic IOP measurement of 22, and then I had a fundus stereophotograph that showed a C/D of 0.3, no nerve fiber defects and suspicious optic discs. I am not too nearsighted, why do I have a fissure? Is there a connection between fissure and IOP? Caiyu, Ophthalmology Department, Peking University First Hospital: With only one pneumatic IOP of 22mmHg, and no changes in the optic nerve fiber layer or optic disc, glaucoma is unlikely. If you are still worried about this year, you can review the fundus photography again, which can detect glaucoma changes earlier. It is recommended to go to an ophthalmology department that specializes in glaucoma for a review, including fundus photography and visual field. Also although high myopia is a risk factor for retinal rupture and retinal detachment, low myopia can also cause it. In the presence of a rupture hole, low intraocular pressure can result from retinal detachment due to the rupture hole.