Patient: Description of the condition (onset time, main symptoms, hospital visited, etc.): Hello, Director Tao: I am a patient in Harbin, more than 10 days ago at your clinic, when measured blood pressure of 135/88, daily self-test low pressure in 90-100, high pressure is not high, the mother side of the family more suffer from hypertension. She took Cordovan and compound date palm capsule according to your medical advice. After taking the medicine, the effect of lowering blood pressure was good, mostly within the normal value, but there were two times when the low pressure was still over 90 after dinner, and I still felt slight dizziness and headache after taking the medicine. At that time, only two boxes of Cordovan were prescribed, and we don’t have this kind of medicine for sale on our side, so please tell me how I should use the medicine and treatment next. Tao Bo, Department of Cardiology, Shanghai Ruijin Hospital: In addition to taking medication, you should also pay attention to non-pharmacological treatment, click here to refer to my article “Non-pharmacological treatment for controlling hypertension”. Some patients with mild symptoms disappear after taking them for a period of time. There is no alternative medicine for the time being, so I will have to ask my friend in Shanghai to prescribe some to me and send it to you. Patient: Thank you, Director Tao, for replying late at night. Does my case require lifelong medication? If so, it would be best to find a drug that is easily available on my side of the world, and an imported long-acting drug would be best. Also, what is the biggest benefit of taking imported antihypertensive drugs over domestic ones? Is it correct to say that I can take some domestic drugs if my condition is not serious and then take imported drugs if it is serious? Thank you! Tao Bo, Department of Cardiology, Shanghai Ruijin Hospital: Generally, you need to take medication for life, and each drug has its own characteristics, which cannot be replaced. The biggest advantage of imported antihypertensive drugs over domestic antihypertensive drugs is that the research data is sufficient, so the price is expensive, but in fact the ingredients are the same as domestic ones, there are some differences in the process, the long-term effectiveness is more reliable, the side effects are relatively less (less impurities), but there is no significant difference in clinical application, there are differences are also individual phenomena, some patients are even more adapted to domestic drugs. Patient: Hello, Director Tao, I was consulted about a drug called Biaxin (produced by Zhejiang Kangenbei Pharmaceuticals), which is also doxazosin mesylate tablets, like Cordovan, and is available in our local area. Since I want to take this medicine for the rest of my life, I would like to ask you whether this medicine can replace Cordova. Also, can imported antihypertensive drugs such as Loxoprofen and Dextran be used? Tao Bo, Department of Cardiology, Ruijin Hospital, Shanghai, China: You can try Biaxin to see if it can replace Cordovan, for the reasons detailed previously, depending on your own reaction and effect monitoring. It is important to see if it can replace Cordovan. The effect of Loxodren and Dextran on diastolic blood pressure may not be as good as that of Cordovan, but we cannot rule out individual cases.