Male urethral intubation can be painful to some extent, mainly due to male physiology, and is generally within tolerable limits. The male urethra is long and has three strictures as well as two bends, three strictures in the internal urethra, the membrane and the external urethra, and two bends one bend for the inferior pubic curve and the other bend for the anterior pubic curve, which tend to irritate or damage the mucosa and produce pain when performing urethral intubation. If the patient is concerned about severe pain or is sensitive to pain, lidocaine hydrochloride gel or oxycodone hydrochloride gel can be injected into the urethra. For surgical patients, intubation can be performed under anesthesia, which can significantly relieve pain. If the patient has stones, prostatic hypertrophy, and other diseases, urethral tube insertion can be difficult and can be catheterized with the help of a urethral dilator, and if necessary, an intraurethral surface anesthetic such as oxybutynin hydrochloride gel should be used to relieve the patient’s pain. When a urinary catheter needs to be left in place, attention should be paid to local care, regular cleaning, such as dilute iodophor or potassium permanganate solution, as well as the application of antibiotics to prevent infection. Therefore, male urethral intubation is somewhat painful, which can be tolerated by most patients, and certain measures can also be taken to relieve pain, which in turn leads to the smooth introduction of the urethral tube and allows the patient to improve his urination problems.