Radial styloid stenosing tenosynovitis (orthopedic) is a clinical condition caused by frequent activities of the thumb or wrist, which causes the thumb extensor and thumb extensor tendons to rub against each other repeatedly in the tendon sheath of the radial styloid process for a long time, resulting in a sterile inflammatory reaction of the tendon and tendon sheath, local exudation, edema and fibrosis, thickening of the sheath wall, and local thickening of the tendon, resulting in obstruction of the tendon’s sliding in the tendon sheath. The clinical manifestations are mainly bulging and pain in the radial tuberosity, increased pain when moving the wrist and thumb, and local pressure pain. The disease is most common in middle-aged people and above, more women than men (about 6:1), and is more common in housewives and manual workers (such as textile workers, carpenters and scribes, etc.). The onset of the disease is slow. The disease can be treated satisfactorily with non-surgical treatment. If the disease is recurrent or non-surgical treatment is ineffective, surgical excision of the narrow tendon sheath is feasible and effective.