Feeling something blocking inside the urethra is commonly associated with urethral stones, urethral infection, prostate enlargement, etc. It is recommended that patients visit the urology department and have their symptoms treated according to the different causes. Patients are advised to visit and examine the urology department and take targeted treatment according to different causes to improve clinical symptoms.1. Urethral stones: Urethral stones will show symptoms of difficult urination with painful urination, and in severe cases, acute urinary retention with severe pain in the perineum, and patients will feel something blocking inside the urethra. Surgical treatment is available, such as direct extraction of the stone through the urethral orifice or removal of the stone by pushing it into the bladder and crushing it. At the same time need to drink a lot of water to promote urination, in order to facilitate the discharge of stones out of the body; 2. Urethral infection: may be due to urinary tract infection with symptoms such as frequent urination, urgent urination, painful urination, etc. Patients can not urinate smoothly and feel that the urethra is blocked, need to pay attention to more rest and drink a lot of water. At the same time follow medical advice to use quinolones or cephalosporin antibiotics to control the infection; 3. Prostatic hyperplasia: For male patients, the possibility of prostate hyperplasia needs to be considered. If the prostate enlargement is more serious, the gland presses the urethra or the middle lobe of the prostate protrudes into the bladder, causing urethral blockage, which can lead to difficulty in urination and produce the symptoms of something blocking in the urethra. If the symptoms are mild and do not affect the quality of daily life, no special treatment can be done for the time being. If it is in the acute stage and urinary retention occurs, catheterization and, if necessary, a cystostomy may be required. Drugs can also be used for supplementary treatment, such as tamsulosin hydrochloride extended-release capsules, finasteride tablets, tolterodine tartrate tablets, etc.; 4. Other factors: feeling something blocking inside the urethra is also seen in benign urethral tumors, malignant tumors or urethral foreign bodies. Because of the short urethra and large diameter of the tube in women, foreign bodies can easily enter the urethra and even move to the bladder. Depending on the size, shape and location of the foreign body as well as the anatomical position of the urethra, an appropriate treatment method needs to be selected, such as treating foreign bodies that can be pushed into the bladder under cystoscopy. If the foreign body is adherent or cannot be pushed into the bladder, the foreign body can be removed in the urethra, and urethrotomy is feasible if necessary. You need to pay attention to rest in your life, develop a regular routine, drink more water and pay attention to local hygiene. You also need to avoid staying up late, and try to eat less spicy and irritating foods such as barbecue and chili.