Epilepsy, commonly known as crohn’s disease, occurs most often in children, and the rational use of antiepileptic drugs is the main means of current treatment of epilepsy in children. Specific medication choices are as follows: 1. For generalized seizures or when the classification is unknown, it is recommended to use broad-spectrum antiepileptic drugs, such as valproic acid, topiramate, lamotrigine, levetiracetam, zonisamide, clonazepam, etc. for treatment; 2. For focal seizures or idiopathic generalized tonic-clonic seizures, narrow-spectrum antiepileptic drugs, such as carbamazepine, oxcarbazepine, phenytoin sodium, etc. for treatment; 3. For infants spasticity or epileptic encephalopathy, special medications such as adrenocorticotropic releasing hormone and aminocaproic acid can be used for treatment. Although drug therapy can better control the condition of children with epilepsy, there are also certain adverse effects. For example, for children with myoclonic, akathisia, and atonic seizures, the selection of drugs should pay attention to carbamazepine, oxcarbazepine, phenytoin sodium, and high doses of phenobarbital, which can induce or aggravate myoclonic, akathisia, and atonic seizures. Secondly, note that when phenytoin sodium is applied, it can cause adverse reactions such as hypertrichosis, tremor, gingival hyperplasia, and ataxia in children. If these adverse reactions occur, it is recommended to seek medical attention to adjust the medication regimen. In addition, western medicine can only reduce the seizures, so it is usually necessary to minimize the mental stimulation of children and not to give them too much mental stress to prevent the recurrence of epilepsy.