Pain is a sensation, an unpleasant feeling, and the International Society for the Study of Pain has a clear definition of pain as an unpleasant sensation or experience of the body caused by definite or underlying tissue trauma. Some tissue injuries are visible with our current medical tools and some are undetectable. These traumas cause the body to react and are sensed centrally, and the sensation is unpleasant, annoying, and very uncomfortable. The sensation of pain may vary from person to person, it is only a personal experience, and it is impossible to describe it in a very precise scale when people communicate with each other, but we all know that the pain is unpleasant and very annoying. Pain can be understood in two ways: pain itself is a sensation, tissue injury, disease, or some lesions can cause pain, such as trauma, needles, incision, septicemia, infection, etc. These can cause injury and pain, and pain is only a clinical manifestation at this time. In fact, pain is a normal reaction to nature, since there is an injury, there is definitely pain, discomfort will certainly avoid, this is a normal reaction. Although pain makes people uncomfortable, but if a person does not feel pain that is terrible. Now there is a disease called sweatless painlessness, the patient itself does not feel pain, the injury, even fractures do not feel pain, their own body scars but do not know the pain, tongue bite full mouth bleeding also do not know the pain, this belongs to the congenital genetic disease. According to this, having pain is a good sign that there is something wrong with our organism somewhere, and we need to see a doctor. So pain is a symptom, which part of the organism has pain, the patient should go to the hospital to see a doctor to diagnose what exactly is the problem, to treat this pain early. So, pain is to some extent our normal physiological reaction. All pain has some relation with nerves, not only pain department, but many departments are involved in pain, and there are many diseases that can cause pain. For another kind of beauty, there are some painless ear piercing and painless cosmetic treatments circulating in the society. These are very simple for those of us who are involved in anesthesia and pain management, and we do major surgeries under anesthesia, not to mention a small ear piercing.