Calcium antagonists are commonly used in the treatment of coronary artery disease, and some patients may need to take them for a long time. Calcium antagonists mainly exhibit a membrane stabilizing effect by inhibiting calcium channels and slowing down the inward flow of calcium ions, which play a role in dilating blood vessels and reducing heart rate and myocardial contractility. Taking calcium antagonists may cause side effects such as gastrointestinal discomfort, loss of appetite, fatigue, and slowed heart rate. In the mid-1990s, someone abroad proposed the idea that calcium antagonists have a carcinogenic effect based on the observation of a high incidence of cancer in patients taking calcium antagonists, and this idea has been rejected due to the shortcomings of the research method itself, and other researchers did not reach the same conclusion.