Usually pediatricians use 38.5°C as the cut-off point for taking antipyretic medication. However, we should also know that the purpose of giving fever-reducing medication is to reduce the child’s discomfort caused by the fever. Therefore, it is more important to focus on the specific “person” rather than the body temperature to determine when antipyretic medication is needed. In other words, there is no one-size-fits-all standard, if you feel uncomfortable, you can consider giving medicine, if there is no special discomfort, there is no need to take antipyretic drugs. Generally speaking, the higher the temperature, the greater the likelihood of discomfort. fevers below 38°C rarely cause serious discomfort in children and usually do not require antipyretic medication. However, some children have a temperature of 39°C and are still spry, or have a relatively high temperature but the child is sleeping soundly, in which case antipyretics are not necessary. For some older children, they do not tolerate fever as well as younger children, and they may feel headache and discomfort just after their body temperature reaches 38°C. In this case, there is no need to wait until their body temperature exceeds 38.5°C before giving them medicine. For antipyretic drugs, I recommend acetaminophen and ibuprofen (Merlin), which are the most widely used in pediatrics, both of which are safe and effective antipyretics. The main points of taking antipyretics: 1. The onset of action of oral antipyretics is generally about half an hour. Half an hour after taking the medicine, if the body temperature begins to fall and the baby’s physical condition allows, it can be supplemented by physical cooling. 2, for general fever, if a kind of antipyretic can control the temperature well, it is recommended to use a single drug to reduce fever, so as to avoid confusion between the two drug doses. 3, in order to ensure safety, the use of a single-component antipyretic drug is recommended for fever. If the effect of a single drug to reduce fever is not satisfactory for persistent high fever, the cause needs to be analyzed. If necessary, two antipyretic drugs can be used alternately under the guidance of a pediatrician. The specific practice of alternating medications: after 4 hours of acetaminophen, if you still need medication to reduce fever, you can choose ibuprofen; after 6 hours of ibuprofen, if you still need medication to reduce fever, you can acetaminophen. Please consult your pediatrician before use. 4, these two drugs are widely used in the world, their safety has been proven, please do not refuse to give your baby medication because of excessive worry about side effects.