Most patients with hypertension combined with coronary heart disease will use the following medications: first, aspirin, which has the effect of antiplatelet aggregation and improving microcirculation, and patients with hypertension combined with coronary heart disease need to take aspirin for life. Secondly, statin lipid-regulating drugs, commonly used drugs are atorvastatin and resulvastatin, these drugs are also recommended to be taken year-round, the main purpose of taking this drug is to stabilize thrombotic plaque, prevent further proliferation of thrombotic plaque, but also has the effect of reducing blood lipids. Finally, patients with hypertension combined with coronary artery disease are preferred to choose antihypertensive drugs such as Prilosec and Diphenhydramine, commonly used Prilosec drugs such as Enalapril and Captopril, which have the effect of reducing the risk of death from coronary artery disease. The most commonly used drugs in the diphenhydramine class are nifedipine and amlodipine, which have anti-platelet aggregation effects while lowering blood pressure.