After the application of antiretroviral therapy to HIV-infected patients, the patient’s medication compliance is the key to the success of antiretroviral therapy. Medication adherence, in layman’s terms, means taking the medication properly, taking it as prescribed, and taking it regularly every day. Adherence to medication is driven by the patient’s own willingness to treat the disease. You can use some timing tools such as alarm clock and cell phone to remind yourself to take your medication on time. For children, it is up to the guardian to ensure compliance. You can also share your medication experience with your friends to encourage each other to ensure compliance. Regular follow-ups and visits, as well as communication with doctors to get their affirmation, will increase confidence and adherence to medication.