There are currently five major categories of first-line recommended drugs for the treatment of hypertension, which are the better antihypertensive drug choices. The first category is the dihydropyridine class of calcium antagonists, such as nifedipine, amlodipine, felodipine, lacidipine, etc. Because these drugs have the word dipine in their names, some people also call them dipine drugs. The second class of drugs is ACEI drugs, which is often called the priligy class of drugs, such as enalapril and benazepril. The third class of drugs is ARB drugs also called sartans, mainly valsartan, irbesartan, olmesartan, etc. The fourth category of drugs is beta-blockers, the most commonly used is betalactam, which is generally used in the class of extended-release tablets, that is, metoprolol succinate extended-release tablets. The fifth category is diuretics, the most commonly used diuretic to lower blood pressure is hydrochlorothiazide, and one is indapamide. For first-degree hypertension, you can choose any one of these five drugs for treatment. As the saying goes, whether it is a white cat or a black cat, the one that can catch the mouse is a good cat. So as long as there are no contraindications, any of these drugs can be used. For Grade 2 or higher hypertension, one drug is definitely not enough, and a combination of two or even three antihypertensive drugs is needed to lower blood pressure.