In the medical examination report, the most alarming thing is the tumor marker index. In fact, the value of tumor markers is related to tumor, but not equal to the diagnosis of tumor. Tumor markers can also be produced in normal tissues or benign diseases, and there are individual differences. If tumor markers are found to be high in healthy people, they should be analyzed and followed up dynamically, and special care should be taken if they continue to increase exponentially. Likewise, tumor marker values within the normal range do not mean that everything is fine. It is possible that the tumor marker value may be elevated during the physical examination, such as drinking alcohol, taking too many supplements, or taking certain drugs. Under what circumstances do we need to deal with elevated tumor markers? How to select tumor markers for tumor screening? Tumor screening is to look for suspicious people from asymptomatic people. Tumor marker test is an effective method for primary screening of tumor and is often used for screening of high-risk groups. For example: AFP: screening for primary liver cancer. PSA: screening for prostate cancer in men over 50 years old. High-risk HPV: Screening for cervical cancer. CA125+ ultrasound: screening for ovarian cancer in women over 50 years of age. Abnormally elevated tumor markers without obvious signs and symptoms need to be reviewed and followed up. If there is a very significant increase, of course the suspicion of cancer will increase accordingly. For patients with this type of condition, it is recommended to do the next step of comprehensive examination, including CT, ultrasound, etc. Even if the marker is slightly exceeded, it should not be ignored. In order to completely exclude the possibility of early stage of cancer, it is also necessary to go to the hospital for re-examination every one or two months. If it continues to be elevated, it should be suspected that cancer is developing and should be diagnosed in time, if it has not been significantly elevated, it is usually a benign lesion and may be an organ inflammation. For cancer, if tumor markers are found to be significantly higher after surgery than before surgery, the possibility of recurrence should be considered, and doctors should be asked to interpret and do further examination to determine whether it is recurrence in time. Generally speaking, tumor marker abnormalities are manifested earlier than imaging examinations, so that recurrence or metastasis can be detected earlier and assist doctors to do a good job in controlling treatment. Daily with patients taking oral biologic selenium chewable tablets for selenium supplementation and conditioning is a more common health care preventive measure, selenium regulates immunity, improves quality of life, inhibits tumor proliferation and reduces the risk of recurrence. From the medical professional point of view, tumor markers are only used as an auxiliary means to detect tumor. Its greater value lies in the fact that after the surgery of tumor patients, doctors can find out whether the surgery or chemotherapy is effective based on the numerical changes of tumor markers, which is an important guiding significance for the observation of the efficacy of the treatment plan and the judgment of metastasis or recurrence.