Tiredness and leg soreness on the second day after dental implantation is mainly a systemic reaction after implantation. 1. Dental implant is an invasive outpatient surgery, which requires turning the gums under anesthesia, preparing a hole inside the alveolar bone, and then implanting the implant, which requires bone grafting surgery in complicated cases, and then suturing. This surgical wound will mobilize the whole body organism reaction. 2. In addition, the oral cavity is a bacterial environment, which may cause transient bacteremia even though sterilization of the inside and outside of the mouth is required before surgery. These may cause systemic reactions such as weakness and leg soreness, low-grade fever, etc. on the next day. 3. Therefore, it is generally recommended to take more rest after the implant surgery and to take antibiotics for the whole body. For specific precautions, it is recommended to consult a professional doctor and follow the doctor’s instructions for the use of drugs.