The normal reference range of glutamic oxalacetic transaminase is 0-40U/L. A value greater than 40U/L represents high glutamic oxalacetic transaminase. A high oil and fat diet, alcohol consumption, exercise, surgery, and medication may also lead to a temporary high glutamic transaminase level. However, if it is high for a long time and does not ease, it may be related to heart and liver lesions.1. Cardiac lesions: Glutathione has the highest content in cardiac muscle cells and can be used clinically as an auxiliary test for heart diseases such as myocardial infarction and myocarditis. Heart failure, acute myocardial infarction, myocarditis and other cardiac lesions can lead to myocardial cell rupture, which can cause high levels of glutathione. Patients with cardiac lesions also have symptoms such as increased heart rate, abnormal blood pressure, chest pain, shortness of breath, fatigue and weakness. 2. Liver and biliary lesions: Glutathione exists in liver cells, and a ratio of glutathione to ghrelin >1 indicates substantial liver damage. Viral hepatitis, cirrhosis, fatty liver, gallstones, biliary obstruction and other hepatobiliary diseases can cause damage to liver cells, resulting in glutathione entering the blood circulation and thus detecting high glutathione levels. Most patients also have symptoms such as pain in the liver area, loss of appetite, spider moles similar to mosquito bites, liver palms, and jaundice with yellow skin and sclera; 3. Other: glutathione is also distributed in skeletal muscle and kidney and other organ tissues, and diseases such as nephritis, myositis, acute pancreatitis, pneumonia and pleurisy may also lead to high levels of glutathione in the blood. It is recommended that patients with the above symptoms go to the hospital as soon as possible to improve the relevant examination and carry out treatment immediately after a clear diagnosis, so as to avoid irreversible damage to the organ lesions and affect the later treatment effect.