The so-called obesity is due to the body’s calorie intake exceeds the body’s calorie consumption, excessive calories in the body into a large number of fat accumulation, is a modern lifestyle disease. At present, the specific method of measuring obesity is as follows: weight more than 20% of the standard weight is called obese. Standard weight (kg) = height (cm) – 105, the ideal weight in the standard weight of ± 10% or less. The actual weight exceeds the standard weight of 10%-20% for overweight, more than 20%-30% for mild obesity, more than 30%-50% for moderate obesity, more than 50% for severe obesity. Obesity not only affects the beauty of the body, and bring inconvenience to life, more importantly, can lead to a series of serious complications, such as hypertension, diabetes, dyslipidemia, coronary heart disease, malignant tumors (such as breast cancer, ovarian cancer, colorectal cancer and prostate cancer) and so on, accelerating aging and death, is the great enemy of health and longevity. The American Diabetes Association reports that the risk of diabetes increases twofold in mildly obese people, fivefold in moderately obese people, and tenfold in severely obese people. This shows that there is a very close relationship between obesity and type 2 diabetes. So why are obese people prone to diabetes? The fundamental reason is that obese people have a special pathology in their bodies called insulin resistance. Insulin is the main blood sugar-lowering hormone in the body. After eating, people absorb a large amount of sugar into the blood and transport it to all parts of the body through blood circulation. Only by relying on insulin can blood sugar enter the cells and be used by the body, while the level of glucose in the blood is maintained within a certain range by insulin. Insulin binds to the insulin receptors on the cell membrane in order to work, and then a series of intracellular signaling substances are involved to transmit the news that “sugar is coming” layer by layer to the depth of the cell, and then a substance called “glucose transporter” is mobilized from the depth of the cell to the surface of the cell membrane. Then, a substance called “glucose transporter” is mobilized from deep inside the cell to the surface of the cell membrane, through which glucose is transported into the cell and used to produce energy. The glucose that is not used at the moment is then converted into glycogen and stored. Unfortunately, in obese people, the above glucose transporter mechanism has many problems, and the cells are resistant to the action of insulin, so it is difficult for the glucose in the blood to enter the cells. This is the phenomenon of insulin resistance. Although the function of insulin secretion in early obesity is still normal, the efficiency of insulin action decreases due to insulin resistance. In order to overcome insulin resistance, the pancreas will synthesize a large amount of insulin, resulting in the blood insulin level of obese people is much higher than that of ordinary people, which is called “hyperinsulinemia”. In the early stage of obesity, it is still possible to maintain blood glucose in the normal range through hyperinsulinemia, but then it is possible that due to overwork, the function of the pancreas to synthesize insulin will gradually fail, and insulin production will gradually be insufficient to lower blood glucose to the normal range, so there will be overt diabetes. Therefore, obesity is very easy to cause diabetes. The incidence of coronary heart disease is two to four times higher in obese people than in lean people. Effective weight loss can prevent the occurrence of diabetes or significantly reduce the degree of diabetes, and the risk of coronary heart disease can be reduced by 35-45% if the weight can be controlled within the normal range. The two main components of obesity treatment are reducing caloric intake and increasing caloric expenditure. A comprehensive treatment based on behavior, diet and exercise is emphasized, supplemented by medication when necessary. The most cost-effective way is undoubtedly to control diet combined with exercise therapy. A controlled diet can include low-fat, low-sugar, high-fiber foods. Exercise can reduce body weight, increase muscle utilization of glucose, reduce insulin resistance, and lower blood sugar; it can also improve the body’s lipid metabolism, improve blood lipid levels, lower blood pressure, exercise the heart and lung function, and improve immunity; it can also cultivate morale, cultivate interest in life, relax tension, and improve the quality of life. Exercise therapy and diet management are the two cornerstones of diabetes treatment. In many patients with milder disease, diet management and moderate exercise alone can bring the disease under effective control.