Erectile dysfunction (ED for short) refers to men’s inability to obtain proper hardness or sufficient erection time during intercourse, thus failing to obtain a satisfactory sex life, causing distress to the couple’s life and often secondary to serious psychological disorders. Due to its unique privacy, the exact incidence is difficult to obtain, but with the accelerated pace of social life and the increased pressure of people’s daily work and life, the incidence is on an increasing trend, which seriously affects people’s physical and mental health and endangers the harmony and happiness of families. It is estimated that about 50% of men at some point in their lives have experienced erectile dysfunction. Men are born with a strong sense of dominance in social and family life, which makes them more likely to become victims of these factors; coupled with smoking, excessive alcohol consumption, irregular or unreasonable eating (excessive intake of spicy and stimulating, oily food), irregular work and rest and lack of necessary exercise can have a huge negative impact on men’s bodies and minds, and become a trigger for ED. However, during the treatment process, we often find numerous patients lacking the necessary understanding of drug effects, adverse reactions and methods of administration, which affects their efficacy. Here, I would like to highlight a few common clinical questions to help patients using this drug. First, the mechanism of action of all PDE5 inhibitors is to induce erection by affecting the local nitric oxide and phosphodiesterase activity of the penile corpus cavernosum, causing relaxation of the smooth muscle of the penile corpus cavernosum and filling of the penile corpus cavernosum blood vessels, so it does not contain any hormones; second, the use of Viagra should be appropriate half to one hour before intercourse, but some people have statistics that even after taking 3-4 or even 5-6 hours Third, before taking, it is best not to drink alcohol and eat too much fatty food; after eating, it is best to wait for 3-4 hours to wait for the stomach food to be properly digested and emptied after taking will play a better role; fourth, after taking the drug, there must be appropriate sexual stimulation (preferably coitus) to induce a good erection; without sexual stimulation, the penis will not naturally erect Fifth, some patients often ask whether taking the medicine can achieve a cure. Is it necessary to take it for life? On this question, I think the efficacy varies from person to person according to the specific situation of each person and the severity of the disease. I know that for mild to moderate and even some severe patients, as long as the treatment according to a reasonable course of treatment, the cure for ED is not impossible to achieve. Of course, this process requires a certain amount of time and enough patience, expecting in a relatively short period of time or 2-3 tablets of drugs to achieve good results is unrealistic. In short, as long as the doctor-patient close cooperation, to establish a good atmosphere of mutual trust, mutual communication, ED treatment will be very good results.