Parkinson’s disease is a common disease in the elderly population, the onset of which is mainly due to the reduction of dopamine synthesis in the patient’s body, manifested by symptoms such as hypermobility, tremor, and body rigidity. Many patients with Parkinson’s disease have obtained great improvement through medication in the early stage. How to use the medication scientifically and correctly? Parkinson’s drugs in general are divided into six major categories. First, anticholinergic drugs, mainly for patients with tremors. Benzedrine, this drug is mainly effective for tremor, but it is not suitable for the elderly, because it will affect the cognition and memory of the elderly, and also increase the side effects of constipation. In addition, some people may induce glaucoma, so generally speaking, we do not recommend the elderly to use, if you really want to use, but also to be more cautious. Second, amantadine amantadine can improve the symptoms of Parkinson’s disease, tonicity, tremor are improved. In particular, in recent years, it has been found that after long-term use of levodopa preparations, some xerostomia can occur, that is, an increase in movement, some uncontrollable, abnormal movements that they can not control such a performance, amantadine still has a certain degree of efficacy, and in recent years it may be found to control this aspect of the symptoms. Third, compound levodopa preparations The most important drug we call levodopa preparations, is the most basic and effective drug for the treatment of Parkinson’s syndrome, tremor, tonicity, motor retardation, etc., have better efficacy, we have two domestic drugs dobutamine, carzodopa. Fourth, dopamine receptor agonists Most of the non-ergot dopamine receptor agonists are currently recommended as the drug of choice, especially for the early stage of the disease process in patients with early onset. We currently have pramipexole and piribedil in China, in addition to the drug ropinirole. Another drug called rotigotine, a patch, can effectively relieve the symptoms of Parkinson’s and can also greatly stop the progression of Parkinson’s disease. Fifth, maob inhibitors. maob inhibitors is monoamine oxidase B inhibitors, here we now have two domestic drugs, one is called Silegiline, is the first generation, and another is just last year on the market called Rexagiline, is the second generation of drugs. These two drugs, on the one hand, are said to have the potential to slow the progression of the disease, on the other hand, can also improve some of the movement disorders of Parkinson’s disease, of course, its efficacy is relatively weaker. Sixth, comt inhibitors catechol-oxygenation-methyltransferase inhibitors: one of the main drugs is called entacapone, which is not effective, but it can increase or enhance the efficacy of levodopa, so it is often used in combination with dobutamine and levodopa, which may increase the efficacy or prolong the efficacy, playing such a role. The principle of Parkinson’s disease medication early treatment, early medication As we all know, medicine is three parts toxic, especially for Parkinson’s disease requires patients to use long-term medication to control the development of the disease. Many patients with Parkinson’s disease are therefore hesitant to take medication. The director of the Department of Neurosurgery at Shanxi Provincial People’s Hospital, Ma Jiuhong, stressed that once Parkinson’s patients are diagnosed, they should take medication as early as possible. Early treatment may interrupt the progressive process of the vicious cycle of Parkinson’s disease, which means that we use drugs early and it may slow down the development. Monoamine oxidase B inhibitors may have the effect of slowing down the rate of progression of Parkinson’s disease. This enables the use of medication for a relatively longer period of time, rather than a large, rapid dose that leads to complications within a short period of time. However, some patients, such as actors, important leaders or people in charge of the company’s facade, may have higher self-image requirements and motor symptoms at social events and may use slightly higher doses of medication. Overall, if there are no special requirements, it is recommended to use as little medication as possible to control symptoms. Scientific reduction and discontinuation of medication Patients with Parkinson’s disease may need to adjust the dosage of medication according to changes in specific symptoms during the long-term course of taking medication. Here it is important to avoid sudden withdrawal of medication and gradually reduce the dosage to discontinuation to avoid or reduce the side effects and complications of medication as much as possible. The treatment process should be individualized to avoid postponing or reducing the side effects and motor complications of medication as much as possible.