The severity of the disease is related to factors such as symptoms and timely treatment, and it is impossible to judge the severity of the disease based solely on the disease suffered, and rheumatism and rheumatoid are two different diseases. Rheumatism refers to chronic painful symptoms in the joints and surrounding soft tissues due to certain causes and can include a variety of diseases, while rheumatoid rheumatism is often manifested as rheumatoid arthritis. Clinically, it is usually necessary to distinguish the difference between the two when patients have inflammatory joint lesions: a. Rheumatism: 1. Clinical manifestations: can occur at all ages, patients can show recurrent episodes of wandering, multiple joint pain, mostly involving larger joints, such as the knee, ankle, followed by the shoulder, elbow, etc. Small joint involvement in the hands and feet is less common. In addition to pain, it may be accompanied by redness, swelling, localized fever, and impaired movement, etc. It usually has a chronic course and may alternate between attacks and remissions, but joint deformities are not usually left after the disappearance of joint symptoms. Some serious patients can also lead to the weakening of internal organs, such as rheumatic heart disease; 2, treatment: rheumatism is often related to streptococcal infections, can follow medical advice for targeted drug treatment. Actively give anti-streptococcal infection treatment, penicillin treatment is the most effective, if there is penicillin allergy, can use cephalosporins or erythromycin drugs anti-infection treatment. At the same time, anti-rheumatic therapy can be given to relieve the symptoms of joint involvement, commonly used drugs include aspirin, prednisone, dexamethasone, etc. Patients should also ensure rest and avoid stimulation, and most patients can recover after active and reasonable treatment is usually given. Rheumatoid arthritis: 1. Clinical manifestations: It occurs in middle-aged women, and the clinical manifestations of rheumatoid arthritis vary greatly among individuals. Usually the onset of the process is slow, the patient will gradually feel the hands, wrists, feet and other joint swelling and pain aggravated, but also accompanied by morning stiffness, that is, morning stiffness of the joints, after activity can be reduced. Joint pain is symmetrical, persistent pain with pressure pain, mostly involving small peripheral joints, patients will also appear joint swelling and deformity, etc., serious cases can involve other systems; 2, treatment: due to the complex etiology of unknown, clinically currently can not cure rheumatoid arthritis. Usually as well as early treatment, adequate attainment, individualized treatment as the principle, in order to achieve the purpose of reducing the risk of disability. Commonly used drugs for the treatment of this disease are methotrexate, leflunomide, etc.