Zhengzhou People’s Hospital December 13, 2014 Zhengzhou People’s Hospital Brain Hospital Zhang Dongfeng December 9 Zhengzhou People’s Hospital Parkinson’s Hepatoparasitic Nuclear Degeneration Ward came to a special patient. The patient’s family made an appointment by phone in advance, specially rushed from the field to find Zhang Dongfeng, director of the clinic, a little after noon, he was tied by six family members sent to the hospital has been waiting for director Zhang’s office, director Zhang to give him a diagnosis during the period, he has been struggling to run out of the house, and his mouth also kept chanting “don’t kill me”! “Don’t kill me,” or some such nonsense. This is a Parkinson’s disease patient, 42 years old, in another hospital for thalamus destruction surgery, however, after the operation, tremor, tonus and these symptoms did not see a significant improvement, but the emergence of hallucinations, hallucinations and other symptoms. The patient’s family described that he always said that he could see strange foreign objects and hear the sound of others trying to harm him. Two days ago for fear of his family to kill him and drive a car, running in the city to 140 yards per hour, due to speeding by the traffic police stopped before stopping. When he saw his family, he got out of the car and ran away, repeating the words “they are going to kill me” as he ran. The family members began to think that the tears and laughter, but the more I think the more fear: the patient has a mental disorder, in this case, if a traffic accident how to do? Later, the family sent him to a psychiatric hospital, two days after treatment, the symptoms did not get relief, but continued to deteriorate. The anxious family members immediately transferred him to the Parkinson’s hepatomegaly ward of our hospital for specialized treatment. After the patient was admitted to the hospital, he was able to cooperate with his family to eat on the same night after systematic intensive treatment, and his mental symptoms were significantly improved. After the patient’s family learned about the patient’s condition, they regretted very much the destruction surgery they had done before. Mr. Zhang Dongfeng, the director of the hospital, introduced that disfigurement surgery is a permanent and irreversible disfigurement surgery, and the efficacy of the surgery depends on various factors such as the mastery of the indications, the severity of the disease, the operator’s technical skills and the comprehensive treatment after the surgery. According to the analysis of domestic and foreign data, the immediate postoperative efficacy is relatively satisfactory, but the long-term efficacy is poor, and it is easy to have complications such as hemiplegia, hemianopsia, dysphagia, speech disorders, balance disorders, easy to fall, mental disorders and so on. Furthermore, drug therapy is no longer effective for a significant portion of postoperative patients for unknown reasons, which increases the difficulty of treatment to a great extent. Currently, disfigurement has been replaced by deep brain stimulation (DBS or brain pacemaker) therapy and is no longer used as clinical treatment. Therefore, Director Zhang suggests Parkinson’s patients and their families to avoid disfiguring surgery when treating them. As the only national tertiary hospital specialty in Henan Province that carries out DBS treatment, our hospital is also the only center in Henan Province that carries out DBS post-operative program control. Director Zhang Dongfeng said that the most important treatment for Parkinson’s disease is individualized drug and DBS treatment, which is the only effective surgical treatment recommended by the FDA and China Parkinson’s disease treatment guidelines, and the inventor of DBS treatment was awarded the Lasker Prize for Clinical Medicine in the U.S., which is known as the “Nobel wind vane”. DBS is another important milestone in Parkinson’s treatment after levodopa. Tiantan Hospital of Capital Medical University conducted a study on 1,086 patients and confirmed that DBS treatment has significant improvement in short-term and long-term efficacy for symptoms such as tremor, tonus, sleep, defecation, pain, anxiety disorders, etc. DBS treatment has the characteristics of completely reversible, non-destructive, adjustable, safe, effective, minimally invasive, etc., which is a treatment method worth to be popularized. (Zhengzhou People’s Hospital, Dongfeng Zhang, Yaru Ji)