The actual dermatologist’s professional perspective on these skin lesions that manifest as white spots is now explained. The so-called white spots, as the name implies, is the skin becomes white, manifested as hypopigmentation or pigmentation loss, many patients equate the white spots with “vitiligo”, in fact, there are many kinds of skin diseases that manifest as white spots. Mostly no self-conscious symptoms pathogenesis: currently unclear. Related tests: Wood lamp, immune function, autoantibodies, trace elements, thyroid antibodies, etc. (because vitiligo can be accompanied by other autoimmune diseases). The actual treatment: according to the duration of the disease, skin distribution, etc. to develop a treatment plan, the goal is to avoid the lesion area continues to expand, promote pigment regeneration, often need several methods of combined treatment (recommended outpatient interview, develop a specific treatment plan), the relative treatment time is long, need to have patience. 2, simple furuncle clinical performance: clinically more common, typical lesions for the edge blurred round or oval hypopigmented spots, which can be covered with a little bran-like scales. The number of lesions is variable, mainly distributed in the face. There is no conscious symptom, and it can be aggravated in summer. Related examination: fungal microscopy, etc. Treatment: Most of them can subside naturally, and weak glucocorticoid ointment, sulfur cream, tacrolimus cream, etc. 3. Clinical manifestations of anaplastic nevi: they appear at birth or soon after birth, and can expand with body development. It appears as pale hypopigmented spots of different sizes, different from vitiligo, often with incomplete depigmentation, blurred and irregular boundaries, sometimes with serrated edges. Related examination: Wood lamp. Treatment: No special treatment, clinical observation is sufficient.4. Clinical manifestations of anemic nevus: Like anaplastic nevus, it appears at birth or soon after birth, showing hypopigmented spots, and after hard rubbing, the lesions are not locally red, but the surrounding skin is red. Related examination: wood, etc. Treatment: No special treatment, clinical observation is sufficient. 5. Hypopigmented clinical manifestations after treatment of lichen planus: Many patients with lichen planus, after antifungal treatment, are left with hypopigmented spots, which sometimes become parasitic white spots. Related tests: fungal microscopy. Treatment: If the microscopic examination is free of lichen planus, a follow-up visit is sufficient. This article is authorized by Dr. Ruzeng Xue.