I. Symptoms Patients with acute onset, fever and rapid progression to high fever, accompanied by malaise, headache, myalgia, sore throat, etc.; and may appear nausea, vomiting, abdominal pain, diarrhea, skin rash, etc.. The disease may enter the extreme stage after the 3rd-4th day, with persistent high fever, increased symptoms of infection toxicity and gastrointestinal symptoms, and various degrees of bleeding, including skin and mucous membrane bleeding, vomiting blood, hemoptysis, blood in stool, and hematuria. Severe cases may have impaired consciousness, shock and multi-organ involvement, and mostly die from bleeding and multi-organ dysfunction within 2 weeks after the onset of the disease. General examination 1.C blood routine: early leukocytes decrease, after the 7th day of illness, rise, and appear heterogeneous lymphocytes, platelets may decrease. 2.C urine routine: proteinuria may be present in the early stage. 3, C biochemical examination: AST and ALT are elevated, and AST elevation is greater than ALT. Pathogenetic examination. 4.C viral antigen: Since Ebola hemorrhagic fever has high titer viraemia, ELISA and other methods can be used to detect viral antigen in the serum. 5, C nucleic acid detection: using RT-PCR and other nucleic acid amplification methods to detect. Viral nucleic acid can generally be detected in the serum of patients within one week after the onset of the disease. 6, C virus isolation: Collect serum specimens from patients within one week of onset and use Vero cells for virus isolation. 7.C-specific IgM antibody: IgM capture ELISA can be used. 7-10 days after symptom onset C-specific IgG antibody: ELISA, immunofluorescence, etc. were used.