Large vestibular aqueduct (LVA) is the most common inner ear malformation, characterized by progressive, fluctuating, and sensorineural deafness. LVA is more common in infants and young children, and is slightly more common in females than males. The clinical diagnosis of LVA has been increasing with the development of imaging and hearing screening in newborns and children. Most children with the disease require hearing aids, but these children may experience fluctuations in hearing due to any cause of increased intracranial pressure, which may result in greater damage to the limited residual hearing, so personal protection should be emphasized in daily life. Mainly include the following aspects: 1, strict prevention of head trauma, do not participate in strenuous physical activities, to prevent the head upside down, do not force to hold their breath, and do any breath-holding activities, including bowel movements. 2, try to prevent and control colds, do not blow your nose or cough hard. 3.If hearing loss occurs again on the basis of the original, you should go to the hospital in time, according to the treatment of sudden deafness, the application of vasodilators, neurotrophic agents, and the use of steroid hormones if necessary. 4, do not use ototoxic drugs aminoglycoside antibiotics, such as: streptomycin, kanamycin, tunicamycin, macromycin, neomycin, gentamicin, vidomycin, cisulmisin (Zithromycin, cisulmomycin), little nosocomial, acemicin (butylaminoacarbamycin), nertilimycin (Knight, Lixixin, Noda), ribofuranoxin, love big (etimicin sulfate), Ikesha (isopamycin sulfate) , Pediatric Lipitor (Gentamicin Sulfate) (used to treat diarrhea, still available in the market), etc.. If hearing changes or tinnitus occurs after using any medicine, the medicine should be stopped promptly to assess whether there is ototoxicity. 5. Stay away from noise. 6, educate children to pay attention to hearing changes, if necessary, you can use the volume size of the cell phone to try, timely detection of fluctuations in hearing, and timely treatment. Although there is a large vestibular aqueduct this birth defect, but clinical I see many children with hearing in addition to poorer, most of them are very smart, so parents and children should face the reality, as far as possible, the use of existing hearing, use a good hearing aid, can still be successful in school, career.