Heart failure is a serious cardiovascular disease, and the goal of treatment is to slow the progression of heart failure, but not to cure it completely. Treatments for heart failure can provide significant symptomatic relief, and although there is no cure, they can extend the life expectancy of patients. Heart failure is the end stage of cardiovascular disease, coronary artery disease, hypertension, valvular disease and other diseases are the main cause of chronic heart failure, when there are infections, exertion, emotional stress, weather changes, arrhythmia and other triggers and can make the acute onset of chronic heart failure. The treatment of acute heart failure should control the underlying disease, eliminate the triggers, improve the symptoms, quickly stabilize the condition, and reduce the damage to other organs. The treatment of chronic heart failure should control the underlying disease, avoid the triggers, anti-failure, improve the prognosis of the treatment, according to the different conditions through oral or intravenous drug delivery, and choose the appropriate type of drugs and dosage to improve the symptoms, improve the prognosis, as far as possible to minimize the incidence of acute heart failure, to maintain the stabilization of the condition of chronic heart failure. Some causes can be improved, such as infection control, blood volume control, emotional and physical activity control, etc. However, the causes of heart failure, such as coronary artery disease, hypertension, valvular disease, etc., cannot be cured, and heart failure will continue to develop. Pharmacological and non-pharmacological treatments for heart failure can better control the heart failure and improve the prognosis, and the condition can be stabilized through treatment, but it is still not completely curable. End-stage refractory heart failure can be considered to be treated by heart transplantation, but the transplantation still has the problems of donor and immune rejection to be solved.