Chest pain is a common clinical symptom, when it occurs people most often think of heart disease and go to cardiology specialists. Others are misdiagnosed by doctors as angina and treated with coronary artery-dilating drugs, but the effect is not obvious, and even the symptoms worsen, thus carrying a heavy burden of thought. Experts point out that chest pain may not always be caused by heart disease. There are many causes of chest pain, in addition to coronary heart disease, pleurisy, lung disease, costochondritis, herpes zoster and other diseases, esophageal chest pain is also a common cause. There are many diseases that cause esophageal-derived chest pain, besides esophageal cancer, esophageal hiatal hernia, cardia failure, diffuse esophageal spasm and other diseases, more common is gastroesophageal reflux disease. The esophagus starts from the epiglottis and passes through the thoracic cavity, connecting with the stomach at the cardia, which can cause chest pain when the esophageal wall is irritated. Gastroesophageal reflux disease produces significant chest pain due to irritation of chemoreceptors in the lower esophagus by chemicals such as gastric acid, bile acid and pancreatic enzymes, as well as esophagitis and ulcers caused by constant reflux. ”Properly understanding esophageal-derived chest pain and identifying the difference between this kind of chest pain and angina will help patients clearly choose a hospital or specialty, get timely treatment and get out of the shadow of so-called ‘heart disease’.” Gastroenterologists say that angina rarely lasts more than 30 minutes and is often combined with palpitations and chest tightness, and the application of drugs such as nitroglycerin can relieve the pain. In contrast, the chest pain caused by GERD often lasts longer, and the pain is related to the position, more pronounced in the lying position than in the standing position. He also stressed that no matter what kind of chest pain occurs, you should not take medication on the basis of symptoms alone, you must go to a regular hospital in time for symptomatic treatment!